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Mesona J is a skincare treatment that delivers beauty ingredients tailored to your skin concerns Mesona J is a skincare treatment that delivers beauty ingredients tailored to your skin concerns

What is Mesona J?

Mesona J is the world’s first transdermal delivery device with high safety, meeting strict medical device quality standards (JIS standards, EMC testing, etc.).
It uses electroporation technology to deliver active ingredients to the dermal layer.
The effects vary depending on the treatment area and the ingredients used.

What is the Mesoporation Method?

Pen-type probe
The pen-type probe uses electroporation to create temporary openings in the skin’s cell membranes, allowing active ingredients to penetrate into the deeper layers of the skin.
Pen-type probe
Roller-type probe
Using a roller-type probe, the treatment employs electrical repulsion, penetration, and physical pressure to deliver high-molecular active ingredients deep into the skin—ingredients that cannot penetrate the skin when simply applied.
Roller-type probe

What is the Electroporation Method?

This is a treatment method in which a mild electrical current is applied to the skin to create tiny openings, allowing the introduction of skincare serums.

Electroporation Method

5 Specialized Courses for Different Concerns

At our clinic, we offer three courses tailored to your skin type: Mesona Yellow for brightening, Mesona Orange for anti-aging, and Mesona Pink for redness.

In addition, we have added two new courses: the Mesona J Special Course, which includes all of the above treatments, and the ultimate anti-aging option, the Mesona J Stem Cell Course. Altogether, we now offer five courses to meet your skincare needs.


Before & After Photos


Pricing for Mesona J

Whitening Course (Mesona Yellow)
Anti-Aging Course (Mesona Orange)
Redness Course (Mesona Pink)		 One session ¥15,000
(¥16,500tax included)
Special Course (Targets all: spots, redness, and fine lines) One session ¥18,000
(¥19,800tax included)
Stem Cell Course One session ¥30,000
(¥33,000tax included)

Discounted multi-session tickets are also available



Treatment Flow

  1. 01 Consultation with a doctor

    Consultation with a doctor

  2. 02 Explanation of the procedure and signing of the consent form

    Explanation of the procedure and signing of the consent form

  3. 03 Face Wash

  4. 04 Skin Analysis Device (Review)

    We will take images using a skin analysis device that can examine your skin condition in detail.

    Detailed Review of the Skin Analysis Machine

    Skin Analysis Device (Review)

  5. 05 Confirm Your Course Based on the Skin Analysis Results

    Confirm Your Course Based on the Skin Analysis Results

  6. 06 Remove only your top and attach the electrode pads.

  7. 07 Wipe again with toner

    Wipe again with toner

  8. 08 Treatment Start

    Using pen-type and roller-type probes, the solution is carefully delivered to the face and neck.

    Treatment Start

  9. 09 Wipe off the solution and apply a pack for about 5 minutes.

    A pack containing active ingredients is applied to help them penetrate deeper into the skin.

    Pack with active ingredients

  10. 10 gentle head massage

    We provide a gentle head massage to relieve your fatigue.

  11. 11 Finishing

    We take care of your skin to keep it healthy and smooth.

Treatment Time about 60 minutes
Pain minimal
Side effects / Risks none
Makeup can be applied immediately after treatment
Bathing allowed from the same day
Side effects / Risks There are generally no side effects or risks; however, the treatment may not be suitable for the following individuals:
・Those with pacemakers, implanted defibrillators, metal plates, or gold threads (dental metals or implants are acceptable)
・Individuals with severe heart disease or diabetes
・Those with large scar tissue or infectious skin conditions in the treatment area
・Individuals prone to keloids
・Pregnant or breastfeeding women"
About Mesona J At our clinic, we provide private medical treatments using devices and medications that have not been approved by the government (domestically unapproved treatments).
This device is not approved in Japan and has been obtained from Serena Medical Co., Ltd.
Public relief systems (Relief System for Adverse Drug Reactions / Relief System for Damage from Biological Products, etc.) do not apply to unapproved drugs and devices.
Currently, there is no safety information available from other countries.

For inquiries by emailFor inquiries by email (for patients and media)